中级职称
李楠 助理教授
电话:0755-26532181           邮箱:lin@szu.edu.cn


     李楠,1983年出生,2013年毕业于北京协和医学院,获得理学博士学位。20138月至201512月在纽约Population council/Rockefeller university从事博士后研究。20161月受聘于香港大学生命科学院,担任研究助理。20163月起受聘于深圳大学生命与海洋科学学院,担任助理教授。

    攻读博士学位和从事博士后研究期间的主要研究方向为男性生殖生物学,所研究的课题主要集中于细胞骨架相关蛋白在精子发生过程中的作用。目前研究的方向是阿尔兹海默症病理过程中神经元突触损伤的机制,以及细胞骨架相关蛋白对于神经元突触可塑性的调节机制。近年来以第一作者发表SCI文章12篇,中文核心期刊论文3篇,以共同作者发表SCI论文8篇。

 

近期代表性论文:

1: Li N,Mruk DD, Tang EI, Lee WM, Wong CK, Cheng CY. Formin 1 regulatesmicrotubule and F-actin organization to support spermatid transport duringspermatogenesis in the rat testis. Endocrinology. 2016 May 4:en20161133. [Epubahead of print] PubMed PMID: 27145014.

 

2: Li N, Cheng CY. Mammalian target of rapamycin complex (mTOR) pathway modulatesblood-testis barrier (BTB) function through F-actin organization and gapjunction. HistolHistopathol. 2016 Mar 9:11753. [Epub ahead of print]
Review.PubMed PMID: 26957088.

 

3: Li N, Mruk DD, Lee WM, Wong CK, Cheng CY. Is toxicant-induced Sertoli cellinjury in vitro a useful model to study molecular mechanisms in spermatogenesis? Semin Cell Dev Biol. 2016 Jan 15. pii: S1084-9521(16)30003-9.doi:10.1016/j.semcdb.2016.01.003. [Epub ahead of print] Review. PubMed PMID:26779951.

 

4: Li N, Mruk DD, Mok KW, Li MW, Wong CK, Lee WM, Han D, Silvestrini B, Cheng CY.Connexin 43 reboots meiosis and reseals blood-testis barrier followingtoxicant-mediated aspermatogenesis and barrier disruption. FASEB J.
2016Apr;30(4):1436-52. doi: 10.1096/fj.15-276527. Epub 2015 Dec 17. PubMed PMID:26678449; PubMed Central PMCID: PMC4799501.

 

5: Li N, Tang EI, Cheng CY. Regulation of blood-testis barrier by actin bindingproteins and protein kinases.Reproduction. 2016 Mar;151(3):R29-41. doi:10.1530/REP-15-0463. Epub 2015 Dec 1. Review. PubMed PMID: 26628556; PubMedCentral PMCID: PMC4780571.

 

6: Li N, Wong CK, Cheng CY. Plastins regulate ectoplasmic specialization via its actin bundling activity on microfilaments in the rat testis. Asian J Androl.2015Nov 20.doi: 10.4103/1008-682X.166583. [Epub ahead of print] PubMed PMID:26608945.