副高职称
肖时锋 特聘副教授
电话:0755-26532181           邮箱:sxiao@szu.edu.cn

    肖时锋,19848月出生,2006年本科毕业于中国科学技术大学化学系,2012年毕业于美国纽约州立大学石溪分校,获博士学位,2012-2015年美国康奈尔医学院博士后研究员,2015年至今深圳大学生命与海洋科学学院任讲师。现担任本科“生物化学”、“生物化学实验”、“分子生物学实验”等教学任务。

    研究工作主要是与阿尔兹海默症相关的蛋白质折叠、蛋白质稳定性、蛋白质结构、蛋白质聚集、蛋白质-蛋白质相互作用等。近年发表SCI论文6篇,包括Proceedings of the National Academy of Sciences of the United States of America, Journal of the American Chemical Society , Journal of Molecular Biology, Journal of Biological Chemistry等高等级SCI期刊。多次参加国际学术会议并做口头或墙报演讲。2015年被认定为深圳市海外高层次人才。


近期发表的代表性论文:


(1) Georgieva ElkaXiao ShifengBorbat PeterFreed Jack(*)Eliezer David(*)Tau binds to lipid membrane surfaces via short amphipathic helices located in its microtubule-binding repeats.Biophysical Journal20141076):1441-1452

 

(2) Xiao Shifeng(#)Patsalo Vadim(#)Shan BingBi YuanGreen DavidRaleigh Daniel(*)Rational modification of protein stability by targeting surface sites leads to complicated  results.Proceedings of the ational Academy of Sciences of the United States of America201311028):11337-11342


(3) Davis CaitlinXiao ShifengRaleigh Daniel(*)Dyer Brian(*)Raising the speed limit for beta-hairpin formation.Journal of the American Chemical Society201213435):14476-14482

(4) Choi UcheorXiao ShifengWollmuth LonnieBowen Mark(*)Effect of Src kinase phosphorylation on disordered C-terminal domain of N-methyl-D-aspartic acid (NMDA) receptor subunit GluN2B protein.Journal of Biological Chemistry201128634):29904-29912

(5) Xiao ShifengRaleigh Daniel(*)A critical assessment of putative gatekeeper interactions in the villin headpiece helical subdomain.Journal of Molecular Biology20104012):274-285

(6) Xiao ShifengBi YuanShan BingRaleigh Daniel(*)Analysis of core packing in a cooperatively folded miniature protein: the ultrafast folding villin headpiece helical subdomain.Biochemistry20094821):4607-4616