DU Xiubo-College of Life and Marine Sciences, Shenzhen University

Dr. Xiubo Du obtained her PhD degree from the University of Hong Kong, at 2011. She worked as a postdoctorial fellow at CAS/Shenzhen University during 2011-2014. Since 2015, she joined the College of Life Sciences and Oceanography, Shenzhen University, as a Lecturer (2015-2018), Associate Research Fellow (2017-2019), Associate Professor (2019-now) and Research Fellow (2021-now). Dr Xiubo Du recently has focused on the pathogenesis and drug development of Alzheimer’s disease (AD) and published a series of papers on TOP journals including Biomaterials, Angew. Chem. Int. Ed., Chem. Commun., Adv. Healthc. Mater. Her research work was financially supported by National Natural Science Foundation of China (NSFC) and the Shenzhen Bureau of Science, Technology and Information. Dr Xiubo Du was awarded Shenzhen Natural Science Second Prize (2017), Shenzhen Overseas High Level Talents (2015) and Shenzhen High Level Talents (2018).

1. Lei Zhang, Penghe Zhao, Caiping Yue, Zhaokui Jin, Qiong Liu, Xiubo Du*, Qianjun He*. “Sustained release of bioactive hydrogen by Pd hydride nanoparticles overcomes Alzheimer's disease”. Biomaterials 2019 Mar;197:393-404. (IF=10.3, JCR一区，TOP期刊)

2. Mengmeng Ma, Nan Gao,* Yuhuan Sun, Xiubo Du,* Jinsong Ren, and Xiaogang Qu*. (2018) “Redox-Activated Near-Infrared-Responsive Polyoxometalates Used for Photothermal Treatment of Alzheimer’s Disease” Adv. Healthc. Mater. doi: 10.1002/adhm.201800320 (IF=6.3, JCR一区，TOP期刊)

3. Du XB, Li HY, Wang XH, Liu Q, Ni JZ and Sun HZ* (2013). "Kinetics and thermodynamics of metal binding to the N-terminus of a human copper transporter, hCTR1" Chem. Commun. 49: 9134-9136. (IF=6.8，JCR一区， TOP期刊)

4. Yongli Xie, Qiong Liu, Lin Zheng, BingTao Wang, Xiaogang Qu, Jiazuan N, Yan Zhang and Xiubo Du*. (2018) “Se-Methylselenocysteine Ameliorates Neuropathology and Cognitive Deficits by Attenuating Oxidative Stress and Metal Dyshomeostasis in Alzheimer Model Mice” Mol. Nutr. Food. Res. DOI: 10.1002/mnfr.201800107 (封面文章，IF=5.2， JCR一区，TOP期刊)

5. Du XB, Zheng YB, Wang Z, Chen YJ, Zhou R, Song GL, Ni JZ* and Liu Q* (2014). "Inhibitory Act of Selenoprotein P on Cu⁺/Cu²⁺-induced tau aggregation and neurotoxicity." Inorg. Chem., DOI: 10.1021/ic501788v. (IF=4.8，JCR一区， TOP期刊)

6. Du XB, Wang Z, Zheng YB, Li HP, Ni JZ* and Liu Q* (2014). "Inhibitory effect of Selenoprotein P on Cu⁺/Cu²⁺-induced Aβ₄₂ aggregation and toxicity." Inorg. Chem., 53 (3): 1672–1678. (IF=4.8，JCR一区，TOP期刊)

7. Li X, Du X*, Ni J. Zn²⁺ Aggravates Tau Aggregation and Neurotoxicity. Int J Mol Sci. 2019 Jan 23;20(3). pii: E487. (IF=4.2, JCR二区，TOP期刊)

8. Xiubo Du^#, Qingqing Shi^#, Yuxi Zhao, Yongli Xie, Xuexia Li, Qiong Liu, Javed Iqbal, Huajie Zhang, Xukun Liu, and Liming Shen*, “Se-Methylselenocysteine (SMC) Improves Cognitive Deficits by Attenuating Synaptic and Metabolic Abnormalities in Alzheimer’s Mice Model: A Proteomic Study” ACS Chem Neurosci 2021 Mar 9. doi: 10.1021/acschemneuro.0c00549. (IF=4.5, JCR二区)

9. Caiping Yue, Zhifu Shan, Yibin Tan, Chuangyu Yao, Yuanheng Liu, Qiong Liu, Xiangshi Tan, Xiubo Du*, “His-Rich Domain of Selenoprotein P Ameliorates Neuropathology and Cognitive Deficits by Regulating TrkB Pathway and Zinc Homeostasis in an Alzheimer Model of Mice”, ACS Chem Neurosci 2020 11(24):4098-4110. (IF=4.5, JCR二区)

10. Yongli Xie, Yibin Tan, Youbiao Zheng, Xiubo Du*, Qiong Liu* (2017). “Ebselen ameliorates β‑amyloid pathology, tau pathology, and cognitive impairment in triple‑transgenic Alzheimer’s disease mice” J. Biol. Inorg. Chem. DOI 10.1007/s00775-017-1463-2 (JCR二区)

11. Du XB, Wang C and Liu Q* (2016). "Potential Roles of Selenium and Selenoproteins in the Prevention of Alzheimer's Disease." Curr. Top. Med. Chem., 2016;16(8):835-48. (JCR二区)

12. Du XB, Li HP, Wang Z, Qiu S, Liu Q* and Ni JZ* (2013). “Selenoprotein P and selenoprotein M block Zn²⁺ -mediated Aβ₄₂ aggregation and toxicity.” Metallomics 5: 861-870. (JCR二区)

13. Du XB, Qiu S, Wang Z, Wang RR, Wang C, Tian J and Liu Q* (2014). "Direct interaction between selenoprotein P and tubulin." Int. J. Mol. Sci. 15 (6): 10199-10214. (JCR三区)

职称	Associate Professor	邮箱	duxiubo@szu.edu.cn
个人简介	Dr. Xiubo Du obtained her PhD degree from the University of Hong Kong, at 2011. She worked as a postdoctorial fellow at CAS/Shenzhen University during 2011-2014. Since 2015, she joined the College of Life Sciences and Oceanography, Shenzhen University, as a Lecturer (2015-2018), Associate Research Fellow (2017-2019), Associate Professor (2019-now) and Research Fellow (2021-now). Dr Xiubo Du recently has focused on the pathogenesis and drug development of Alzheimer’s disease (AD) and published a series of papers on TOP journals including Biomaterials, Angew. Chem. Int. Ed., Chem. Commun., Adv. Healthc. Mater. Her research work was financially supported by National Natural Science Foundation of China (NSFC) and the Shenzhen Bureau of Science, Technology and Information. Dr Xiubo Du was awarded Shenzhen Natural Science Second Prize (2017), Shenzhen Overseas High Level Talents (2015) and Shenzhen High Level Talents (2018).

Associate Professor

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