都秀波-深圳大学生命与海洋科学学院

基本信息

姓名：都秀波
职称：副教授
职位：学科建设办主任
所属系：生物科学系
办公地点：丽湖校区守慧楼609
办公电话：
邮箱：duxiubo@szu.edu.cn
工作职责：

个人简介

都秀波，深圳大学特聘研究员、副教授，留学博士生导师。近年主要从事阿尔茨海默病及抑郁症的发病机制及防治药物研究，在包括Molecular Psychiatry, Advanced Science, Biomaterials, Angew. Chem. Int. Ed., Chem. Commun., Adv. Healthc. Mater.等国际知名期刊发表学术论文五十余篇。主持国家自然科学基金2项，深圳市海外高层次人才启动项目1项及其他省市项目4项，获广东省教育成果二等奖、深圳市自然科学二等奖。入选深圳市海外高层次人才（孔雀计划）、深圳市高层次人才。

近期发表的论文

1. Jiantao Liu^#; Feiyuan Peng^#; Penghui Li; Chuangyu Yao; Sha Jin; Guoli Wu; Tianshu Zhang; Qiulian Liang; Xiaohui Wang*; Xiubo Du*; Mechanistic Insights into Cannabidiol-Mediated TrkB Activation via FRS2 Interaction in Attenuating Alzheimer's Disease Pathology and Cognitive Impairment, Mol Psychiatry, 2026, doi: 10.1038/s41380-026-03525-3. (IF=10.1，JCR一区，NI期刊，TOP期刊)

2. Xiubo Du; Jiantao Liu; Xiaohui Wang*; The transformational power of psychedelics: catalysts for creativity, consciousness, and mental health, Mol Psychiatry, 2025, 30(12): 6165-6171. (IF=10.1，JCR一区，NI期刊，TOP期刊)

3. Penghui Li, Mingsong Shi, Yibo Wang, Qiong Liu, Xiubo Du*, Xiaohui Wang*, “pH-Dependent Assembly and Stability of Toll-Like Receptor 3/dsRNA Signaling Complex: Insights from Constant pH Molecular Dynamics and Metadynamics Simulations”, Adv Sci 2025, 12(1):e2411445. (IF=15.1，JCR一区，TOP期刊)

4. Cong Lin, Xiubo Du and Xiaohui Wang*, “A perspective on Alzheimer’s disease: exploring the potential of terminal/paradoxical lucidity and psychedelics”, Mol Neurodegener 2024 19(1):72. (IF=15.1，JCR一区，TOP期刊)

5. Lei Zhang, Penghe Zhao, Caiping Yue, Zhaokui Jin, Qiong Liu, Xiubo Du*, Qianjun He*. “Sustained release of bioactive hydrogen by Pd hydride nanoparticles overcomes Alzheimer's disease”. Biomaterials 2019 Mar;197:393-404. (IF=10.27, JCR一区，TOP期刊)

6. Xuexia Li, Linfeng Le, Qingqing Shi, Hao Xu, Chao Wang, Yufang Xiong, Xun Wang, Guoli Wu, Qiong Liu and Xiubo Du*, “Zinc exacerbates tau-induced Alzheimer-like pathology in C57BL/6J mice”, Int J Biol Macromol 2023 242(Pt 2):124652. (IF=8.03，JCR一区，TOP期刊)

7. Yongli Xie, Xiaoshan Ke, Zhencong Ye, Xuexia Li, Zetao Chen, Jiantao Liu Guoli Wu, Qiong Liu and Xiubo Du* “Se-Methylselenocysteine Ameliorates Mitochondrial Function by Targeting both Mitophagy and Autophagy in the Model of Alzheimer's Mice”, Food Funct 2024 15(8):4310-4322. (IF=6.1，JCR一区，TOP期刊)

8. Xuexia, Li, Qingqing Shi, Hao Xu, Yufang Xiong, Chao Wang, Linfeng Le, Junliang Lian, Guoli Wu, Feiyuan Peng, Qiong Liu and Xiubo Du*, “Ebselen Interferes with Alzheimer’s Disease by Regulating Mitochondrial Function”. Antioxidants 2022, 11, 1350. (IF=7.68，JCR一区，TOP期刊)

9. Mengmeng Ma, Nan Gao,* Yuhuan Sun, Xiubo Du,* Jinsong Ren, and Xiaogang Qu*. (2018) “Redox-Activated Near-Infrared-Responsive Polyoxometalates Used for Photothermal Treatment of Alzheimer’s Disease” Adv. Healthc. Mater. doi: 10.1002/adhm.201800320 (IF=6.27, JCR一区，TOP期刊)

10. Yongli Xie, Qiong Liu, Lin Zheng, BingTao Wang, Xiaogang Qu, Jiazuan N, Yan Zhang and Xiubo Du*. (2018) “Se-Methylselenocysteine Ameliorates Neuropathology and Cognitive Deficits by Attenuating Oxidative Stress and Metal Dyshomeostasis in Alzheimer Model Mice” Mol. Nutr. Food. Res. 2018 Jun;62(12):e1800107. (封面文章，IF=4.65， JCR一区，TOP期刊)

11. Du XB, Zheng YB, Wang Z, Chen YJ, Zhou R, Song GL, Ni JZ* and Liu Q* (2014). "Inhibitory Act of Selenoprotein P on Cu⁺/Cu²⁺-induced tau aggregation and neurotoxicity." Inorg. Chem., DOI: 10.1021/ic501788v. (IF=4.8，JCR一区， TOP期刊)

12. Du XB, Wang Z, Zheng YB, Li HP, Ni JZ* and Liu Q* (2014). "Inhibitory effect of Selenoprotein P on Cu⁺/Cu²⁺-induced Aβ₄₂ aggregation and toxicity." Inorg. Chem., 53 (3): 1672–1678. (IF=4.8，JCR一区，TOP期刊)

13. Du XB, Li HY, Wang XH, Liu Q, Ni JZ and Sun HZ* (2013). "Kinetics and thermodynamics of metal binding to the N-terminus of a human copper transporter, hCTR1" Chem. Commun. 49: 9134-9136. (IF=6.8，JCR一区，TOP期刊)