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教授

 

  基本信息
  • 姓      名：刘宏涛
  • 职      称：特聘教授
  • 职      位：院长
  • 所  属 系：
  • 办公地点：丽湖校区守慧楼616
  • 办公电话：0755-26558080
  • 邮      箱：htliu@szu.edu.cn
  • 工作职责：教学、科研、行政
  个人简介

刘宏涛，深圳大学生命与海洋科学学院，特聘教授，先后获得国家基金委“杰出青年基金”， “优秀青年基金”，“重点”，“原创探索”，科技部“推进计划”中青年科技创新领军人才，中科院“百人计划”，上海市“优秀学术带头人”、“浦江人才”等项目资助。

长期从植物光信号转导的研究，发现了光和温度协同调控植物发育的分子机制；揭示了植物适应紫外光UV-B水平变化、协调生长和胁迫反应的分子机理；开辟了绿光信号调控植物发育的新研究方向。相关研究以通讯作者在Developmental Cell, Nature Plants, Nature Structure & Molecular Biology, Nature Communications, EMBO J, PNAS, Plant Cell等国际著名学术期刊上发表。相关成果多次受到Developmental Cell, Nature Plants, NSMB, Plant Cell等国际权威学术刊物的专文评述。多篇论文入选ESI高被引论文。担任中国植物生理与分子生物学学会女科学家分会副会长，Plant Cell、Current Biology、中国科学（生命科学）、JIPB、Plant Communications、aBiotech、Frontiers Plant Science杂志编委。获得“中国青年科技奖”，“中国青年女科学家奖”，“中科三安光生物学杰出贡献奖”，“亚太光生物学会青年科学家奖”等奖励。

  近期发表的论文

科研获奖情况

  1. 第十七届中国青年女科学家奖 (2022)

  2. 中科三安光生物学杰出贡献奖 （2020）

  3. 第十六届中国青年科技奖 （2020）

  4. 亚太光生物学青年科学家奖（2019 Asia and Oceania Society for Photobiology Award for Young Scientists）

  5. 2016年 “百人计划终期评估”获得优秀

  6. 2016年度“河北省科学技术奖”二等奖 （排名第三）

  7. 2014年度美国植物生理学会的“Women’s Young Investigator Travel Awards (WYITA) for Plant Biology 2014”奖

  8. 2009 年度美国Parvin 基金会奖 ，加州大学洛杉矶分校（UCLA）最佳生物化学与分子生物学博士后研究奖(2009 Parvin Foundation Award, Best Postdoctoral Research in Biochemistry & Molecular Biology, MBI, University of California, Los Angeles)。

  9. 2009 年度加州大学洛杉矶分校（UCLA）分子生物学博士后研究奖(2009 MBI Postdoctoral Recognition Awards, University of California, Los Angeles)。

  10. 2005 年度河北省自然科学一等奖，获奖项目名称为“热激信号转导的钙-钙调素途径”，第二完成人


主要研究论文:

  1. Yuhan Hao, Zexian Zeng, Xiaolin Zhang, Dixiang Xie, Xu Li, Libang Ma, Muqing Liu and Hongtao Liu*. (2023) Green means go: Green light promotes hypocotyl elongation via Brassinoteroid signaling, Plant Cell, doi: 10.1093/plcell/koad022.

  2. Zhao Zhiwei, Dent Craig, Liang Huafeng, Lv Junqing, Shang Guandong, Liu Yawen, Feng Fan, Wang Fei, Pang Junhong, Li Xu, Ma Libang, Li Bing, Sureshkumar Sridevi, Wan Jia-Weig, Balasubramanian Sureshkumar, and Liu Hongtao*. (2022) CRY2 interacts with CIS1 to regulate thermosensory flowering via FLM alternative splicing, Nature Communications, Nov 17;13(1):7045. doi: 10.1038/s41467-022-34886-2. 2012

  3. Zhenhua Zhang, Chenjie Xu, Shiyu Zhang, Chen Shi, Hong Cheng, Hongtao Liu, Bojian Zhong* （2022） Origin and adaptive evolution of UV RESISTANCE LOCUS 8-mediated signaling during plant terrestrialization. Plant Physiology. 188(1):332-346 doi: 10.1093/plphys/kiab486.

  4. Li X, Liang T, Liu H*. (2022) How plants coordinate their development in response to light and temperature signals. The Plant Cell. (invited review)20;188(1):332-346.

  5. Ma Libang, Li Xu, Zhao Zhiwei, Hao Yuhao, Shang Ruixin, Zeng Desheng, Liu Hongtao*. (2021) Light-Response Bric-A-Brack/Tramtrack/Broad proteins mediate cryptochrome 2 degradation in response to low ambient temperature. The Plant Cell. doi: 10.1093/plcell/koab219

  6. Shi C, Liu H*. (2021) How plants protect themselves from ultraviolet-B radiation stress. Plant Physiology. https://doi.org/10.1093/plphys/kiab245 (invited review)

  7. Liang T#, Shi C#, Peng Y, Tan H, Xin P, Yang Y, Wang F, Li X, Chu J, Huang J, Yin Y, Liu H*. (2020) Brassinosteroid-Activated BRI1-EMS-SUPPRESSOR 1 Inhibits Flavonoid Biosynthesis and Coordinates Growth and UV-B Stress Responses in Plants. The Plant Cell. Oct;32(10):3224-3239. DOI: https://doi.org/10.1105/tpc.20.00048

  8. Xu Li#, Cuicui Liu#, Zhiwei Zhao, Dingbang Ma, Jinyu Zhang, Yu Yang, Yawen Liu, Hongtao Liu*. (2020) COR27 and COR28 are Novel Regulators of the COP1–HY5 Regulatory Hub and Photomorphogenesis in Arabidopsis. The Plant Cell. Oct;32(10):3139-3154 DOI: https://doi.org/10.1105/tpc.20.00195

  9. Shao K#, Zhang X#, Li X#, Hao Y, Huang X, Ma M, Zhang M, Yu F, Liu H*, Zhang P*. (2020) The oligomeric structures of plant cryptochromes. Nature Structure & Molecular Biology. 27: 472–479

  10. Yang Y, Liu H*. (2020) Coordinated shoot and root responses to light signaling in Arabidopsis. Plant Communications, DOI: 10.1016/j.xplc.2020.100026

  11. Yang Y, Zhang L, Chen P, Liang T, Li X, Liu H*. (2020) UVR8 interacts with MYB73/MYB77 in a UV-B-dependent manner, regulating auxin responses and lateral root development. EMBO Journal. 39(2):e101928. doi/10.15252/embj.2019101928

  12. Zhang N, Meng Y, Li X, Zhou Y, Ma L, Fu L, Schwarzlander M, Liu H, Xiong Y. (2019) Metabolite-mediated TOR signaling regulates the circadian clock in Arabidopsis. Proc Natl Acad Sci U S A https://www.pnas.org/content/early/2019/11/27/1913095116

  13. Wang F, Yuan Z, Zhao Z, Li C, Zhang X, Liang H, Liu Y, Xu Q, Liu H*. (2019) Tasselseed5 of maize is a cytochrome C oxidase that affecting jasmonate catabolism in sex determination. Journal of Integrative Plant Biology. https://doi.org/10.1111/jipb.12826

  14. Wang F#, Gao Y#, Liu Y#, Zhang X, Gu X, Ma D, Zhao Z, Yuan Z, Xue H and Liu H*. (2019) BES1 regulated BEE1 controls photoperiodic flowering downstream of blue light signaling pathway in Arabidopsis New Phytologist. DOI: 10.1111/nph.15866

  15. Wang J, Chen S, Jiang N, Li N, Wang X, Li Z, Li X, Liu H, Li L, Yang Y, Ni T, Yu C, Ma J, Zheng B, Ren G*. (2019) Spliceosome disassembly factors ILP1 and NTR1 promote miRNA biogenesis in Arabidopsis thaliana. Nucleic Acids Res. 47(15):7886-7900. doi: 10.1093/nar/gkz526.

  16. Tan Y, Yang Y, Zhang A, Fei CF, Gu L, Sun S, Xu W, Wang L, Liu H, Wang YF*. (2019)Three CNGC Family Members, CNGC5, CNGC6, and CNGC9, Are Required for Constitutive Growth of Arabidopsis Root Hairs as Ca2+-Permeable Channels. Plant Communications. https://doi.org/10.1016/j.xplc.2019.100001

  17. Liang T, Yang Y, Liu H*. (2018) Signal transduction mediated by the plant UV-B photoreceptor UVR8. New Phytologist. 221(3):1247-1252 doi: 10.1111/nph.15469 (Invited review)

  18. Liang T, Mei S, Shi C, Yang Y, Peng Y, Ma L, Wang F, Li X, Huang X, Yin Y, Liu H*. (2018) UVR8 interacts with BES1 and BIM1 to regulate transcription and photomorphogenesis in Arabidopsis. Developmental Cell. 44:1-12 https://doi.org/10.1016/j.devcel.2017.12.028

  19. Yang Y, Liang T, Zhang L, Shao K, Gu X, Shang R, Shi N, Li X, Zhang P, Liu H*. (2018) UVR8 interacts with WRKY36 to regulate HY5 transcription and hypocotyl elongation in Arabidopsis. Nature Plants. doi: https://doi.org/10.1038/s41477-017-0099-0

  20. Liu Y, Li X, Ma D, Chen Z, Wang JW, Liu H*. (2018) CIB1 and CO interact to mediate CRY2 regulation of flowering. EMBO Reports. DOI: 10.15252/embr.201845762

  21. Reqing He#, Xinmei Li#, Ming Zhong#, Jindong Yan, Ronghuang Ji, Xu Li, Qin Wang, Dan Wu, Mengsi Sun, Dongying Tang, Jianzhong Lin, Hongyu Li, Bin Liu, Hongtao Liu, Xuanming Liu*, Xiaoying Zhao*, Chentao Lin, A photo-responsive F-box protein FOF2 regulates floral initiation by promoting FLC expression in Arabidopsis. The Plant Journal, 2017, 91, 788-801

  22. Li X, Cai W, Liu Y, Li H, Fu L, Liu Z, Xu L, Liu H, Xu T, Xiong Y* (2017) Differential TOR activation and cell proliferation in Arabidopsis root and shoot apexes. Proc Natl Acad Sci U S A. 114(10):2765-2770

  23. Li X#, Ma D#, Lu S#, Hu X, Huang R, Liang T, Xu T, Tobin E, Liu H*. (2016) Blue Light- and Low Temperature-Regulated COR27 and COR28 Play Roles in the Arabidopsis Circadian Clock. The Plant Cell. 28(11):2755-2769 doi: http://dx.doi.org/10.1105/tpc.16.00354

  24. Ma D，Li X，Guo Y，Chu J，Fang S，Yan C，Noel J P，Liu H*，(2016) Cryptochrome 1 interacts with PIF4 to regulate high temperature-mediated hypocotyl elongation in response to blue light.，Proc Natl Acad Sci U S A， 113(1)：224-229

  25. Li L, Li X, Liu Y, Liu H*. (2016) Flowering responses to light and temperature. Sci China Life Science. doi:10.1007/s11427-015-4910-8

  26. Gao QF, Gu LL, Wang HQ, Fei CF, Fang X, Hussain J, Sun SJ, Dong JY, Liu H, Wang YF*. (2016) Cyclic nucleotide-gated channel 18 is an essential Ca2+ channel in pollen tube tips for pollen tube guidance to ovules in Arabidopsis. Proc Natl Acad Sci U S A，113(11):3096-101

  27. Zhang TQ, Lian H, Tang H, Dalezal K, Zhou CM, Chen JH, Chen Q, Liu H, Ljung K, Wang JW*(2015). An Intrinsic MicroRNA Timer Regulates Progressive Decline in Shoot Regenerative Capacity in Plants. Plant Cell 27(2) 349-360.

  28. Liu Y, Li X, Li K, Liu H*, Lin C (2013). Multiple bHLH proteins form heterodimers to mediate CRY2-dependent regulation of flowering-time in Arabidopsis, PLoS Genetics 9(10): e1003861

  29. Liu H*, Wang Q, Liu Y, Zhao X, Lin C*(2013). The Arabidopsis photoreceptors CRY2 and ZTL mediate blue-light regulation of the transcription factor CIB1 by distinct mechanisms. Proc Natl Acad Sci U S A 110(43):17582-7

  30. Tan ST, Dai C, Liu HT, and Xue HW* (2013). Arabidopsis casein kinase1 proteins CK1.3 and CK1.4 phosphorylate cryptochrome 2 to regulate blue light signaling. Plant Cell 25(7): 2618-2632.

  31. Liu H*, GomezG, Lin S, Lin S, Lin C (2012). Optogenetic control of transcription in zebrafish. PLoS One. 7(11):e50738. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050738

  32. Wang Q, Fristedt R, Yu X, Chen Z, Liu H Lee Y,Guo H,Merchant SS,Lin C(2012). The γ-carbonic anhydrase subcomplex of mitochondrial complex I is essential for development and important for photomorphogenesis of Arabidopsis. Plant Physiology.160(3):1373-1383

  33. Liu H, Liu B. Zhao C, Pepper M and Lin C (2011). The action mechanisms of plant cryptochromes, Trends in Plant Sciences, 16(12):684-691.

  34. Lu S#, Liu H#, Knowles S, Li J, Ma L, Tobin E, Lin C. (2011). A role for protein kinase CK2 alpha subunits in the Arabidopsis circadian clock. Plant Physiology 157(3): 1537-1545 (co-first author)

  35. Zuo Z#, Liu H#, Liu B#, Liu X, Lin C.(2011) Blue Light-Dependent Interaction of CRY2 with SPA1 Regulates COP1 activity and Floral Initiation in Arabidopsis. Current Biology 21(10):841-847 (co-first author)

  36. Li X, Wang Q, Yu X, Liu H, Yang H et al (2011) Arabidopsis cryptochrome 2 (CRY2) functions by the photoactivation mechanism distinct from the tryptophan (trp) triad-dependent photoreduction. Proc Natl Acad Sci U S A 108(51):20844-20849.

  37. Liu B, Zuo Z, Liu H, Lin C. (2011). Arabidopsis cryptochrome 1 interacts with SPA1 to suppress COP1 activity in response to blue light. Gene & Development 25:1029-1034

  38. Liu B, Liu H, Zhong D, and Lin C. (2010). Searching for a photocycle of the Cryptochrome photoreceptors. Current Opinion in Plant Biology 13(5):578-586

    http://www.sciencedirect.com/science/article/pii/S136952661000124X

  39. Liu H,Yu X, Li K, Klejnot J, Yang H, Lisiero D, Lin C. (2008). Photoexcited CRY2 interacts with CIB1 to regulate transcription and floral initiation in Arabidopsis. Science 322(5907):1535-1539.

  40. Liu HT,Gao F, Li GL, Han JL, Liu DL, Sun DY, Zhou RG. (2008). The calmodulin-binding protein kinase 3 is part of heat-shock signal transduction in Arabidopsis thaliana. The Plant Journal 55(5):760-73.

  41. Liu HT, Li GL, Chang H, Sun DY, Zhou RG, Li B. (2007). Calmodulin-binding protein phosphatase PP7 is involved in thermotolerance in Arabidopsis. Plant Cell & Enviroment 30(2):156-64.

  42. Liu HT#, Gao F#, Sun DY, Zhou RG. (2006). Primary evidence for involvement of IP3 in heat-shock signal transduction in Arabidopsis. Cell Research 16(4):394-400

  43. Liu HT, Sun DY, Zhou RG. (2005). Ca2+ and AtCaM3 are involved in the expression of Heat Shock Protein Gene in Arabidopsis. Plant Cell & Environment 28:1276-1284

  44. Liu HT，Li B, Shang ZL, Mu RL Sun DY, Zhou RG. (2003). Calmodulin is involved in heat shock signal transduction in wheat. Plant Physiology 132(3): 1186-1195.

  45. Li B,Liu HT，Sun DY, Zhou RG. (2004). Ca2+ and Calmodulin modulate DNA-binding activity of maize heat shock transcription factor in vitro. Plant Cell Physiology 45(5): 627-634.

     

专利：

1.刘宏涛，王飞，赵志伟，王正琪，张鑫，梁华峰，调节植物开花及生物量的基因及其利用，专利授权号 ZL201910456537.1，授权公告日2022-5-17

2. 刘宏涛，梁通，史辰，调节植物类黄酮合成及紫外抗性的基因及其利用，专利授权号 ZL 201811049304.1，授权公告日 2023年5月5日

3.刘宏涛，杨郁，MYB与UVR8以UVB依赖形式相互结合来调控植物根的生长发育，专利授权号 ZL20181503981.6，授权公告日 2023年5月9日


代表性论文：

  1. Yuhan Hao, Zexian Zeng, Xiaolin Zhang, Dixiang Xie, Xu Li, Libang Ma, Muqing Liu and Hongtao Liu*. (2023) Green means go: Green light promotes hypocotyl elongation via Brassinoteroid signaling, Plant Cell, doi: 10.1093/plcell/koad022.

  2. Zhao Zhiwei, Dent Craig, Liang Huafeng, Lv Junqing, Shang Guandong, Liu Yawen, Feng Fan, Wang Fei, Pang Junhong, Li Xu, Ma Libang, Li Bing, Sureshkumar Sridevi, Wan Jia-Weig, Balasubramanian Sureshkumar, and Liu Hongtao*. (2022) CRY2 interacts with CIS1 to regulate thermosensory flowering via FLM alternative splicing, Nature Communications, Nov 17;13(1):7045. doi: 10.1038/s41467-022-34886-2. 2012

  3. Yang Y, Zhang L, Chen P, Liang T, Li X, Liu H*. (2020) UVR8 interacts with MYB73/MYB77 in a UV-B-dependent manner, regulating auxin responses and lateral root development. EMBO Journal. 39(2):e101928. doi/10.15252/embj.2019101928

  4. Liang T, Mei S, Shi C, Yang Y, Peng Y, Ma L, Wang F, Li X, Huang X, Yin Y, Liu H*. (2018) UVR8 interacts with BES1 and BIM1 to regulate transcription and photomorphogenesis in Arabidopsis. Developmental Cell. 44:1-12 https://doi.org/10.1016/j.devcel.2017.12.028

  5. Yang Y, Liang T, Zhang L, Shao K, Gu X, Shang R, Shi N, Li X, Zhang P, Liu H*. (2018) UVR8 interacts with WRKY36 to regulate HY5 transcription and hypocotyl elongation in Arabidopsis. Nature Plants. doi: https://doi.org/10.1038/s41477-017-0099-0

 

职称 特聘教授 职位 院长
所属系 办公室 丽湖校区守慧楼616
办公电话 0755-26558080 邮箱 htliu@szu.edu.cn
工作职责 教学、科研、行政 个人简介 <p>刘宏涛，深圳大学生命与海洋科学学院，特聘教授，先后获得国家基金委“杰出青年基金”， “优秀青年基金”，“重点”，“原创探索”，科技部“推进计划”中青年科技创新领军人才，中科院“百人计划”，上海市“优秀学术带头人”、“浦江人才”等项目资助。
<p>长期从植物光信号转导的研究，发现了光和温度协同调控植物发育的分子机制；揭示了植物适应紫外光UV-B水平变化、协调生长和胁迫反应的分子机理；开辟了绿光信号调控植物发育的新研究方向。相关研究以通讯作者在Developmental Cell, Nature Plants, Nature Structure & Molecular Biology, Nature Communications, EMBO J, PNAS, Plant Cell等国际著名学术期刊上发表。相关成果多次受到Developmental Cell, Nature Plants, NSMB, Plant Cell等国际权威学术刊物的专文评述。多篇论文入选ESI高被引论文。担任中国植物生理与分子生物学学会女科学家分会副会长，Plant Cell、Current Biology、中国科学（生命科学）、JIPB、Plant Communications、aBiotech、Frontiers Plant Science杂志编委。获得“中国青年科技奖”，“中国青年女科学家奖”，“中科三安光生物学杰出贡献奖”，“亚太光生物学会青年科学家奖”等奖励。